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CRTC1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 27647-1-AP-20UL
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Description
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites.Acts as a coactivator, in the SIK/TORC signaling pathway,being active when dephosphorylated and acts independently of CREB1 ′Ser-133′ phosphorylation.Enhances the interaction of CREB1 with TAF4.Regulates the expression of specific CREB-activated genes such as the steroidogenic gene,StAR.Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells.Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintece at the Schaffer collateral-CA1 synapses.May be required for dendritic growth of developing cortical neurons.Spécification
| CRTC1 | |
| Polyclonal | |
| Unconjugated | |
| CRTC1 | |
| CRTC1, KIAA0616, MECT1, TORC 1, TORC1, Transducer of CREB protein 1, WAMTP1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 23373, 382056 | |
| -20°C | |
| Liquid |
| Western Blot | |
| 0.4 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q68ED7, Q6UUV9 | |
| Crtc1 | |
| CRTC1 Fusion Protein Ag26494 | |
| 20 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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