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Thermo Scientific Chemicals SB 225002

Product Code. 15486869
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Quantité:
5 mg
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Un puissant antagoniste compétitif sélectif du récepteur couplé aux protéines G, le CXCR2

SB 225002 is a selective non-peptide CXCR2 inhibitor which suppresses IL-8 induced neutrophil chemotaxis and margination. In addition, SB 225002 reduces MPO activity, IL-1β, MIP-2, and keratinocyte-derived chemokine (KC) levels. Further studies suggest that SB 225002 decreases the expression of vascular endothelial growth factor, inducible NOS (NO synthase), and Cox-2 (cyclooxygenase-2 proteins) in colon tissue.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 182498-32-4
Formule moléculaire C13H10BrN3O4
Synonyme 1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea

Specifications

Quantité 5 mg
Description Jaune
Contenu et stockage -30°C à -10°C
À utiliser avec (application) Puissant antagoniste sélectif et compétitif du récepteur couplé aux protéines G CXCR 2
Poids de la formule 352,10g/mol
Sensibilité Sensible à l’humidité
Solubilité Soluble à 100 mM dans le DMSO et à 50 mM dans l’éthanol
Type de produit Signal Transduction Reagent
Forme Solide

RUO – Research Use Only

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