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SART1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

136.48CHF - 385.92CHF

Specifications

Antigen SART1
Concentration 0.33 mg/mL
Applications Immunoprecipitation, Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16812045
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Proteintech
22675-1-AP-20UL
20 μL
136.48CHF
20µL
Only null left
Estimated Shipment: 23-07-2025
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16802045
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Proteintech
22675-1-AP-150UL
150 μL
385.92CHF
150µL
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In Stock
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Description

Description

This antibody recognizes the endogenous 800-amino acid SART1, which migrates with an apparent molecular mass of 110 kDa in SDS-PAGE.

This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.
Specifications

Specifications

SART1
Immunoprecipitation, Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
Rabbit
Human, Mouse
O43290, Q9Z315
20227, 9092
SART1 Fusion Protein Ag18478
Primary
-20°C
SART1
0.33 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Ara1, Hom s 1, HOMS1, hSART 1, hSnu66, SART 1, SART1, SART1259, SNRNP110, Snu66, SNU66 homolog
SART1
IgG
Antigen Affinity Chromatography
Antibody
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SDS
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