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NRF2/NFE2L2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 16396-1-AP-20UL
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Description
Nrf2 (nuclear factor erythroid 2-related factor 2) is a transcription activator which plays a key role in protecting the cell from oxidative stress and inflammation. It is primarily localized in the cytoplasm under normal conditions, but under conditions of oxidative stress, Nrf2 migrates to the nucleus to upregulate expression of genes with ARE (antioxidant response elements) in the promoter region. The upregulated genes include those involved in cellular protection, drug transport, detoxification, and anti-oxidant defense. The protein is ubiquitously expressed in various tissues, with the highest levels found in kidney, muscle, lung, heart, liver, and brain.Specifications
| NRF2/NFE2L2 | |
| Polyclonal | |
| Unconjugated | |
| NFE2L2 | |
| HEBP1, NF E2 related factor 2, NFE2 related factor 2, NFE2L2, NRF2 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 18024, 4780, 83619 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin) | |
| 0.47 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| O54968, Q16236, Q60795 | |
| Nfe2l2 | |
| NRF2, NFE2L2 Fusion Protein Ag9489 | |
| 20 μL | |
| Primary | |
| Human, Rat, Mouse | |
| Antibody | |
| IgG |
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