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Invitrogen™ Human MAP3K11 (MLK3), GST Tag Recombinant Protein
Recombinant Protein
Marque: Invitrogen™ PV3788
Description
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Full Length
MAP3K11 (MLK3) is a serine/threonine kinase that activates both the p38 MAP kinase and c-Jun kinase pathways. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.
Spécification
Q16584 | |
Kinase Assay | |
4296 | |
Human MAP3K11 (MLK3), GST Tag | |
2610017K16Rik; MAP3K11; MEKK11; MGC17114; mitogen activated protein kinase kinase kinase 11; mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Mlk3; MLK-3; protein-tyrosine kinase PTK1; PTK1; RHOE; SH3 domain-containing proline-rich kinase; SPRK; Src-homology 3 domain-containing proline-rich kinase | |
MLK Kinase Family | |
Human | |
GST-tag | |
-80°C, Avoid Freeze/Thaw Cycles | |
Ser⁄Thr Kinases: TKL Group | |
LanthaScreen™ Antibody, LanthaScreen™ Substrate, Omnia™ Bulk Substrate | |
mitogen-activated protein kinase kinase kinase 11 | |
Kinases & Inhibitors | |
Liquid | |
Immunology, Oncology, Signal Transduction |
See Label | |
50 mM tris with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5 | |
120.1 kDa | |
10 μg | |
MLK3 | |
Unconjugated | |
Recombinant | |
Full length | |
Biochemical terbium phospho-specific activity, Biochemical binding/kinetic | |
Dry Ice | |
MAP3K11 | |
Insect cells | |
Recombinant, Full Length | |
Serine/Threonine Kinases |
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