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Forskolin, Tocris Bioscience™
Adenylyl cyclase activator
229.00€ - 890.00€
Identifiants chimiques
| CAS | 66575-29-9 |
|---|---|
| Formule moléculaire | C22H34O7 |
| Poids moléculaire (g/mol) | 410.507 |
| Clé InChI | OHCQJHSOBUTRHG-KGGHGJDLSA-N |
| Synonyme | forskolin, colforsin, coleonol, colforsina, colforsine, colforsinum, boforsin, colforsine french, colforsinum latin, colforsina spanish |
| CID PubChem | 47936 |
| ChEBI | CHEBI:42471 |
| Nom IUPAC | Acétate [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-éthényl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentaméthyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] |
| SMILES | CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O |
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|---|---|---|---|---|---|---|---|---|---|
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|
18782764
|
Tocris Bioscience
1099/10 |
10 mg |
229.00€
10mg |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | |||||
|
30001193
|
Tocris Bioscience
|
50 mg |
890.00€
50mg |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | |||||
Description
Forskolin, or coleonol, is a cell-permeable, potent, reversible and rapid activator of adenylyl cyclase, an enzyme that converts ATP to cAMP and pyrophosphate (EC50 = 0.5 μM). In combination with 5 other compounds, forskolin enables chemical reprogramming of mouse embryonic fibroblasts to pluripotent stem cells, without genetic factors: Valproic acid, sodium salt (Cat. No. 2815), RepSox (Cat. No. 3742), Tranylcypromine hydrochloride (Cat. No. 3852), CHIR 99021 (Cat. No. 4423) and 3-Deazaneplanocin A hydrochloride (Cat. No. 4703). In combination with IBMX (Cat. No. 2845), forskolin induces neural differentiation of mesenchymal stem cells by downregulating neuron restrictive silencer factor. In a rat model of Huntington's disease-like neurodegeneration, forskolin also exhibits neuroprotective effects. Hypotensive and vasodilatory agent.Water-soluble analog, NKH 477 (Cat. No. 1603), and Forskolin synthesized to Ancillary Material Grade also available.
For more information about how Forskolin may be used, see our protocol: Transdifferentiating Fibroblasts into Neurons.
Identifiants chimiques
| 66575-29-9 | |
| 410.507 | |
| forskolin, colforsin, coleonol, colforsina, colforsine, colforsinum, boforsin, colforsine french, colforsinum latin, colforsina spanish | |
| CHEBI:42471 | |
| CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O |
| C22H34O7 | |
| OHCQJHSOBUTRHG-KGGHGJDLSA-N | |
| 47936 | |
| Acétate [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-éthényl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentaméthyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] |
Spécification
| (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one | |
| C22H34O7 | |
| OHCQJHSOBUTRHG-KGGHGJDLSA-N | |
| Acétate [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-éthényl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentaméthyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] | |
| 47936 | |
| 410.51 |
| 66575-29-9 | |
| forskolin, colforsin, coleonol, colforsina, colforsine, colforsinum, boforsin, colforsine french, colforsinum latin, colforsina spanish | |
| CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O | |
| 410.507 | |
| CHEBI:42471 | |
| >98% |
Safety and Handling
Recommended Storage : Desiccate at -20°C
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