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C4 alpha chain/C4b/C4d Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00€ - 410.00€

Specifications

Antigen C4 alpha chain/C4b/C4d
Concentration 0.25 mg/mL
Applications Immunoprecipitation, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16851775
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Proteintech
22233-1-AP-20UL
20 μL
145.00€
20µL
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16841775
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Proteintech
22233-1-AP-150UL
150 μL
410.00€
150µL
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Description

Description

This antibody raised against 1017-1336aa of human C4-A protein can recognize C4 precursor, C4 alpha chain, C4b, and C4d.

This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene.
Specifications

Specifications

C4 alpha chain/C4b/C4d
Immunoprecipitation, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Rabbit
Human
P0C0L4
720
C4 alpha chain/C4b/C4d Fusion Protein Ag17583
Primary
-20°C
C4A
0.25 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Acidic complement C4, C4, C4A, C4A2, C4A3, C4A4, C4A6, C4S, CO4, Complement C4 A, CPAMD2, RG
C4A
IgG
Antigen Affinity Chromatography
Antibody
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