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ADAM10 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 25900-1-AP-20UL
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Description
Proinflammatory cytokine tumor necrosis factor-a (TNF-a) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-a, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-a, notch and its ligand delta (1-3). The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM 10, kuzbanian (KUZ), and MADM, respectively. ADAM10 mRNA is expressed in a variety of human and bovine tissues.Spécification
| ADAM10 | |
| Polyclonal | |
| Unconjugated | |
| ADAM10 | |
| AD10, ADAM 10, ADAM10, CD156c, CDw156, HsT18717, kuz, Kuzbanian protein homolog, MADM | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 102, 11487 | |
| -20°C | |
| Liquid |
| Western Blot, Immunohistochemistry (Paraffin) | |
| 0.2 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| O14672, O35598 | |
| ADAM10 | |
| ADAM10 Fusion Protein Ag23078 | |
| 20 μL | |
| Primary | |
| Mouse, Human | |
| Antibody | |
| IgG |
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