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ACE2 Mouse anti-Human, Clone: 2F12A4, Proteintech

Mouse Monoclonal Antibody

145.00€ - 410.00€

Specifications

Antigen ACE2
Clone 2F12A4
Concentration 1 mg/mL
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16828825
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Proteintech
66699-1-IG-20UL
20 μL
145.00€
20µL
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16818825
View Documents
Proteintech
66699-1-IG-150UL
150 μL
410.00€
150µL
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Description

Description

This antibody is specific to ACE2.

Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.
Specifications

Specifications

ACE2
1 mg/mL
Monoclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
ACE related carboxypeptidase, ACE2, ACEH, DKFZp434A014, Metalloprotease MPROT15
ACE2
IgG1
Protein G
Antibody
2F12A4
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Mouse
Human
Q9BYF1
59272
ACE2 Fusion Protein Ag15554
Primary
-20°C
ACE2
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